MONOTERPENOID INDOLE ALKALOIDS FROM ALSTONIA YUNNANENSIS AND THEIR CYTOTOXIC AND ANTI-INFLAMMATORY ACTIVITIES

Monoterpenoid Indole Alkaloids from Alstonia yunnanensis and Their Cytotoxic and Anti-inflammatory Activities

The 80% ethanol extract of Alstonia yunnanensis afforded five new monoterpenoid indole alkaloids: 11-hydroxy-6,7-epoxy-8-oxo-vincadifformine (1), 14-chloro-15-hydroxy- vincadifformine (2), perakine N4-oxide (3), raucaffrinoline N4-oxide (4), and vinorine N1,N4-dioxide (5), together with three Dry Mouth Remedies known compounds: 11-methoxy-6,7-epoxy

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Prebiotic supplementation in frail older people affects specific gut microbiota taxa but not global diversity

Abstract Background There are complex interactions between aging, frailty, diet, and the gut microbiota; modulation of the gut microbiota by diet could lead to healthier aging.The purpose of this study was to test the effect of diets differing in sugar, fat, and fiber content upon the gut microbiota of mice humanized with microbiota from healthy or

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